
Unique hepatic-derived surgical matrix primed for cellular integration
MiroFlex™ (formerly known as MiroMesh) is a non-crosslinked acellular surgical matrix, derived from the highly vascularized porcine liver. It is intended for implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair such as hernia repairs or reinforcement in plastic and reconstructive surgery. If larger sizes of MiroFlex are desired, pieces may be quilted together.
Histologic evaluation of MiroFlex biologic matrix revealed enhanced recellularization with evidence of long-term remodeling and tissue alignment, supporting the mechanical data.
STUDY | AUTHOR | PUBLICATION | FULL ARTICLE |
An in vivo analysis of MiroFlex (formerly known as MiroMesh) – a novel porcine liver prosthetic created by perfusion decellularization | Clayton C. Petro, MD | Journal of Surgical Research 2016;201:29-37 | Read Here |
A comparative analysis of ventral hernia repair with a porcine hepatic-derived matrix and porcine dermal matrix | Job Tharappel | International Journal of Abdominal Wall and Hernia Surgery 2019;2(3):89-95 | Read Here |
A multi-center, prospective clinical trial of a hepatic derived porcine surgical mesh for the laparoscopic repair of symptomatic paraesophageal hernias | Michael J. Rosen | The American Journal of Surgery 2019;218(2):315-322 | Read Here |
Retrospective review and prospective follow-up of 85 consecutive patients treated with a novel hepatic-derived surgical mesh for hiatal hernia repair: outcomes, surgical complications, and revisions | George K. Gillian, MD | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2019;29(6):529-533 | Read Here |
TITLE | PHYSICIAN | ASSOCIATION | DATE | VIDEO |
Reducing Failure Rates in Hiatal and Paraesophageal Hernia Repair – the ‘Achilles Heel’ of Anti-reflux Surgery | Dr. G. Kevin Gillian | Florida Chapter, American College of Surgeons |
01/19/2021 | ![]() Watch Here |
ITEM ID | SIZE | TOTAL cm2 |
BLM-100-01-0608 | 6cm x 8cm | 48 |
BLM-100-01-0808 | 8cm x 8cm | 64 |
BLM-100-01-1010 | 10cm x 10cm | 100 |
BLM-100-01-0816 | 8cm x 16cm | 128 |
BLM-100-01-1016 | 10cm x 16cm | 160 |
BLM-100-01-1020 | 10cm x 20cm | 200 |
MiroFlex is processed and stored in a phosphate buffered aqueous solution, packaged in an inner sterile pouch and outer non-sterile pouch, and sterilized with electron beam irradiation. MiroFlex comes in a variety of sizes and is intended for use only by trained medical professionals who are familiar with surgical procedures and techniques involving a surgical matrix. Federal (U.S.A) law restricts this product to sale by or on the order of a physician.
MiroMesh is now MiroFlex. MiroFlex Biologic Matrix is intended to be implanted to reinforce soft tissue and is also intended for implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair or reinforcement in plastic and reconstructive surgery.
See IFU for full prescribing information, including indications, contraindications, precautions, and potential complications.

A vessel on the open edge of MiroFlex was cannulated and a red dye was injected into the graft to demonstrate the presence of the native liver vasculature, including the capillaries.
MiroFlex is clinically proven for hiatal and paraesophageal hernia repair
- Unique hepatic-derived surgical matrix with natural vascular pathways
- Native vasculature is preserved down the the capillary beds (250 µM)
- Open vascular pathways assist in facilitating cellular integration and remodeling in surgical use
Designed for surgical success

Our Technology
Our proprietary process removes cellular material from complex, highly vascularized organs, such as the liver. The result is an architecturally intact collagen scaffold with pre-existing vascular pathways.
Product Inquiries and Orders
Call us at: 763-284-6780
Fax us at: 952-856-5085
Product Inquiries at: customerservice@reprisebio.com
SM-00154 Rev. D 01/21