The Only Hepatic-Derived Surgical Matrix Primed for Cellular Integration

MIROMESH® is a non-crosslinked acellular surgical mesh, derived from the highly vascularized porcine liver. It is intended to be implanted to reinforce soft tissue and is also intended for implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair such as hernia repairs, or reinforcement in plastic and reconstructive surgery. If larger sizes of MIROMESH are desired, pieces may be quilted together.

Histologic evaluation of MIROMESH biologic matrix revealed enhanced recellularization with evidence of long-term remodeling and tissue alignment, supporting the mechanical data.

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STUDY AUTHOR PUBLICATION FULL ARTICLE
An in vivo analysis of MIROMESH – a novel porcine liver prosthetic created by perfusion decellularization Clayton C. Petro, MD Journal of Surgical Research  2016;201:29-37 Read Here
A comparative analysis of ventral hernia repair with a porcine hepatic-derived matrix and porcine dermal matrix Job Tharappel International Journal of Abdominal Wall and Hernia Surgery 2019;2(3):89-95 Read Here
A multi-center, prospective clinical trial of a hepatic derived porcine surgical mesh for the laparoscopic repair of symptomatic paraesophageal hernias Michael J. Rosen The American Journal of Surgery 2019;218(2):315-322 Read Here
Retrospective review and prospective follow-up of 85 consecutive patients treated with a novel hepatic-derived surgical mesh for hiatal hernia repair: outcomes, surgical complications, and revisions George K. Gillian, MD Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2019;29(6):529-533 Read Here

 

ITEM ID SIZE TOTAL cm2
BLM-100-01-0608 6 x 8 cm 48
BLM-100-01-0808 8 x 8 cm 64
BLM-100-01-1010 10 x 10 cm 100
BLM-100-01-0816 8 x 16 cm 128
BLM-100-01-1016 10 x 16 cm 160
BLM-100-01-1020 10 x 20 cm 200

MIROMESH is processed and stored in a phosphate buffered aqueous solution, packaged in an inner sterile pouch and outer non-sterile pouch, and sterilized with electron beam irradiation. MIROMESH comes in a variety of sizes and is intended for use only by trained medical professionals who are familiar with surgical procedures and techniques involving surgical mesh. Federal (U.S.A) law restricts this product to sale by or on the order of a physician.

The MIROMESH Biologic Matrix is intended to be implanted to reinforce soft tissue and is also intended for implantation to reinforce soft tissue where weakness exists in patients requiring soft tissue repair or reinforcement in plastic and reconstructive surgery. 

See IFU for full prescribing information, including indications, contraindications, precautions, and potential complications.

A vessel on the open edge of MIROMESH was cannulated and a red dye was injected into the graft to demonstrate the presence of the native liver vasculature, including the capillaries.

Designed for Soft Tissue Reinforcement

  • For use in open and laparoscopic hiatal, paraesophageal, parastomal, and ventral hernia repairs
  • Ability to be custom shaped and fit through a laparoscopic trocar
  • Can be quilted together to reinforce larger hernias

MIROMESH has natural vascular pathways and an open collagen matrix that assist in facilitating cellular integration and remodeling in surgical use.

 

Our Technology

Our perfusion decellularization technology facilitates rapid access to the whole organ. By cannulating the native vasculature and perfusing a mild detergent solution through the native blood vessels. This is in contrast to immersing the organ as in immersion decellularization. 

Product Inquiries and Orders

Call us at: 763-284-6780

Fax us at: 952-856-5085

Product Inquiries at: customerservice@reprisebio.com

SM-00154 Rev. A 05/20

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